Pharmacokinetics of plasma-derived C1-esterase inhibitor after subcutaneous versus intravenous administration in subjects with mild or moderate hereditary angioedema: the PASSION study

BACKGROUND: Hereditary angioedema (HAE) is a rare disease caused by C1-esterase inhibitor (C1-INH) deficiency, characterized by periodic attacks of acute edema affecting subcutaneous (SC) tissues and mucous membranes. Human C1-INH concentrate given intravenously (IV) is effective and safe, but venou...

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Detalhes bibliográficos
Main Authors: Martinez-Saguer, Inmaculada, Cicardi, Marco, Suffritti, Chiara, Rusicke, Eva, Aygören-Pürsün, Emel, Stoll, Hildegard, Rossmanith, Tanja, Feussner, Annette, Kalina, Uwe, Kreuz, Wolfhart
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Transfusion Practice
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215596/
https://ncbi.nlm.nih.gov/pubmed/24266596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.12501
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