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Asymmetric Carbamoyl Anion Additions to Chiral N-Phosphonyl Imines via the GAP Chemistry Process and Stereoselectivity Enrichments

[Image: see text] Carbamoyl anions were found to smoothly react with chiral N-phosphonyl imines in toluene at −78 °C to r.t. using LiHMDS as the base. Group-assisted purification (GAP) has been utilized to give the pure amides without using column chromatography or recrystallization. The asymmetric...

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書目詳細資料
發表在:J Org Chem
Main Authors: Seifert, Cole W., Pindi, Suresh, Li, Guigen
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285137/
https://ncbi.nlm.nih.gov/pubmed/25458404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo5024443
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