Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis

An FAD-dependent monooxygenase encoding gene (SorbC) was cloned from Penicillium chrysogenum E01-10/3 and expressed as a soluble protein in Escherichia coli. The enzyme efficiently performed the oxidative dearomatisation of sorbicillin and dihydrosorbicillin to give sorbicillinol and dihydrosorbicil...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Fahad, Ahmed al, Abood, Amira, Fisch, Katja M., Osipow, Anna, Davison, Jack, Avramović, Marija, Butts, Craig P., Piel, Jörn, Simpson, Thomas J., Cox, Russell J.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2014
Teme:
Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285102/
https://ncbi.nlm.nih.gov/pubmed/25580210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3sc52911h
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