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Oxidative steps during the biosynthesis of squalestatin S1

The squalestatins are a class of highly complex fungal metabolites which are potent inhibitors of squalene synthase with potential use in the control of cholesterol biosynthesis. Little is known of the chemical steps involved in the construction of the 4,8-dioxa-bicyclo[3.2.1]octane core. Here, usin...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Lebe, Karen E., Cox, Russell J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349020/
https://ncbi.nlm.nih.gov/pubmed/30774923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02615g
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