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Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis

A gene cluster encoding the biosynthesis of the fungal tropolone stipitatic acid was discovered in Talaromyces stipitatus (Penicillium stipitatum) and investigated by targeted gene knockout. A minimum of three genes are required to form the tropolone nucleus: tropA encodes a nonreducing polyketide s...

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Detalhes bibliográficos
Main Authors: Davison, Jack, al Fahad, Ahmed, Cai, Menghao, Song, Zhongshu, Yehia, Samar Y., Lazarus, Colin M., Bailey, Andrew M., Simpson, Thomas J., Cox, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356636/
https://ncbi.nlm.nih.gov/pubmed/22508998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201469109
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