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Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia

Cilia dysfunction underlies a class of human diseases with variable penetrance in different organ systems. Across eukaryotes, intraflagellar transport (IFT) facilitates cilia biogenesis and cargo trafficking, but our understanding of mammalian IFT is insufficient. Here we perform live analysis of ci...

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Vydáno v:Nat Commun
Hlavní autoři: Williams, Corey L., McIntyre, Jeremy C., Norris, Stephen R., Jenkins, Paul M., Zhang, Lian, Pei, Qinglin, Verhey, Kristen, Martens, Jeffrey R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284812/
https://ncbi.nlm.nih.gov/pubmed/25504142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6813
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