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Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy
The human rhodopsin gene is the locus for numerous alleles linked to the neurodegenerative disease retinitis pigmentosa. To facilitate the study of retinal degeneration and to test reagents designed to alter the structure and function of this gene, we have developed strains of mice whose native rhod...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15184660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403149101 |
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