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Synthesis, Docking and Biological Activities of Novel Hybrids Celecoxib and Anthraquinone Analogs as Potent Cytotoxic Agents

Herein, novel hybrid compounds of celecoxib and 2-aminoanthraquinone derivatives have been synthesized using condensation reactions of celecoxib with 2-aminoanthraquinone derivatives or 2-aminoanthraquinon with celecoxib derivatives. Celecoxib was reacted with different acid chlorides, 2-chloroethyl...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Almutairi, Maha S., Hegazy, Gehan H., Haiba, Mogedda E., Ali, Hamed I., Khalifa, Nagy M., Soliman, Abd El-mohsen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284725/
https://ncbi.nlm.nih.gov/pubmed/25490139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151222580
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