DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a singl...

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Vydáno v:Nat Commun
Hlavní autoři: Nguyen, Long V., Cox, Claire L., Eirew, Peter, Knapp, David J. H. F., Pellacani, Davide, Kannan, Nagarajan, Carles, Annaick, Moksa, Michelle, Balani, Sneha, Shah, Sohrab, Hirst, Martin, Aparicio, Samuel, Eaves, Connie J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284657/
https://ncbi.nlm.nih.gov/pubmed/25532760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6871
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