DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a singl...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nguyen, Long V., Cox, Claire L., Eirew, Peter, Knapp, David J. H. F., Pellacani, Davide, Kannan, Nagarajan, Carles, Annaick, Moksa, Michelle, Balani, Sneha, Shah, Sohrab, Hirst, Martin, Aparicio, Samuel, Eaves, Connie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284657/
https://ncbi.nlm.nih.gov/pubmed/25532760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6871
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