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microRNAs: short non-coding bullets of gain of function mutant p53 proteins

TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single aminoacid change and are abundantly present in cancer cells. Some of mutant p53 proteins gain oncogenic activities through which actively contribute to the aberrant cel...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoscience
Hauptverfasser: Donzelli, Sara, Strano, Sabrina, Blandino, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284623/
https://ncbi.nlm.nih.gov/pubmed/25594041
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