Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors

RNA-binding motif protein 38 (Rbm38), also called RNPC1 [RNA-binding region (RNP1, RRM) containing 1], is a target of the p53 family and modulates p53 expression via mRNA translation. To investigate the biological function of Rbm38 in vivo, we generated an Rbm38-null mouse model. We showed that mice...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Zhang, Jin, Xu, Enshun, Ren, Cong, Yan, Wensheng, Zhang, Min, Chen, Mingyi, Cardiff, Robert D., Imai, Denise M., Wisner, Erik, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284600/
https://ncbi.nlm.nih.gov/pubmed/25512531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415607112
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