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Disruption of the Rbm38-eIF4E complex with a synthetic peptide Pep8 increases p53 expression

Rbm38 is a p53 target and a RNA-binding protein known to suppress p53 translation by preventing eukaryotic translation initiation factor 4E (eIF4E) from binding to p53 mRNA. In this study, we show that synthetic peptides corresponding to the binding interface between Rbm38 and eIF4E, including an 8...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Lucchesi, Christopher A., Zhang, Jin, Ma, Buyong, Chen, Mingyi, Chen, Xinbin
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377842/
https://ncbi.nlm.nih.gov/pubmed/30591552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2209
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