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Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells

An orthogonal tryptophanyl–transfer RNA (tRNA) synthetase (TrpRS)-mutant opal suppressor tRNA(Trp) ([Formula: see text]) pair was generated for use in mammalian cells. The anticodon loop of the Bacillus subtilis tRNA(Trp) was mutated to UCA, three positions in the D arm were mutated to generate an i...

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Detalhes bibliográficos
Main Authors: Zhang, Zhiwen, Alfonta, Lital, Tian, Feng, Bursulaya, Badry, Uryu, Sean, King, David S., Schultz, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC428441/
https://ncbi.nlm.nih.gov/pubmed/15187228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307029101
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