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Enhanced Yield of Recombinant Proteins with Site-Specifically Incorporated Unnatural Amino Acids Using a Cell-Free Expression System

Using a commercial protein expression system, we sought the crucial elements and conditions for the expression of proteins with genetically encoded unnatural amino acids. By identifying the most important translational components, we were able to increase suppression efficiency to 55% and to increas...

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Detalhes bibliográficos
Main Authors: Smolskaya, Sviatlana, Zhang, Zhiwen Jonathan, Alfonta, Lital
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699557/
https://ncbi.nlm.nih.gov/pubmed/23844190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068363
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