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Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21

When human cells incur DNA damage, two fundamental responses can follow, cell cycle arrest or apoptosis. Human RAD9 (hRAD9) and p53 function in both processes, but the mechanistic relationship between their activities is unknown. p53 mediates checkpoint control at G(1) by transcriptional regulation...

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Hlavní autoři: Yin, Yuxin, Zhu, Aiping, Jin, Yan J., Liu, Yu-Xin, Zhang, Xia, Hopkins, Kevin M., Lieberman, Howard B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC428438/
https://ncbi.nlm.nih.gov/pubmed/15184659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403130101
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