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Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21
When human cells incur DNA damage, two fundamental responses can follow, cell cycle arrest or apoptosis. Human RAD9 (hRAD9) and p53 function in both processes, but the mechanistic relationship between their activities is unknown. p53 mediates checkpoint control at G(1) by transcriptional regulation...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC428438/ https://ncbi.nlm.nih.gov/pubmed/15184659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403130101 |
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