Minor antigens on transfused RBCs crossprime CD8 T cells but do not induce full effector function

HLA-matched bone marrow transplantation (BMT) is a cure for nonmalignant hematological disorders; however, rejection rates are high and correlate with the number of antecedent transfusions. Recently, using murine models, we reported that minor antigens (mHAs) in transfused leukoreduced RBC or platel...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Desmarets, Maxime, Mylvaganam, Geetha, Waller, Edmund K., Josephson, Cassandra D., Pack, Christopher, Lukacher, Aron E., Zimring, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284100/
https://ncbi.nlm.nih.gov/pubmed/21884408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03730.x
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