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Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A
We previously identified the NS5A/HSP70 binding site to be a hairpin moiety at C-terminus of NS5A domain I and showed a corresponding cyclized polyarginine-tagged synthetic peptide (HCV4) significantly blocks virus production. Here, sequence comparison confirmed five residues to be conserved. Based...
Tallennettuna:
| Julkaisussa: | Virology |
|---|---|
| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284078/ https://ncbi.nlm.nih.gov/pubmed/25462345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.10.011 |
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