Germline Mutations of Inhibins in Early-Onset Ovarian Epithelial Tumors

To identify novel genetic bases of early-onset epithelial ovarian tumors, we used the trio exome sequencing strategy in a patient without familial history of cancer who presented metastatic serous ovarian adenocarcinomas at 21 years of age. We identified a single de novo mutation (c.1157A>G/p.Asn...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Tournier, Isabelle, Marlin, Régine, Walton, Kelly, Charbonnier, Françoise, Coutant, Sophie, Théry, Jean-Christophe, Charbonnier, Camille, Spurrell, Cailyn, Vezain, Myriam, Ippolito, Lorena, Bougeard, Gaëlle, Roman, Horace, Tinat, Julie, Sabourin, Jean-Christophe, Stoppa-Lyonnet, Dominique, Caron, Olivier, Bressac-de Paillerets, Brigitte, Vaur, Dominique, King, Mary-Claire, Harrison, Craig, Frebourg, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284000/
https://ncbi.nlm.nih.gov/pubmed/24302632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22489
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados