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Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications

As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Rath, Timo, Baker, Kristi, Pyzik, Michal, Blumberg, Richard S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283642/
https://ncbi.nlm.nih.gov/pubmed/25601863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00664
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