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Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications

As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Rath, Timo, Baker, Kristi, Pyzik, Michal, Blumberg, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283642/
https://ncbi.nlm.nih.gov/pubmed/25601863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00664
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