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Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications

As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rath, Timo, Baker, Kristi, Pyzik, Michal, Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283642/
https://ncbi.nlm.nih.gov/pubmed/25601863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00664
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