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Succinate Overproduction: A Case Study of Computational Strain Design Using a Comprehensive Escherichia coli Kinetic Model

Computational strain-design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models. In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations u...

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Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Khodayari, Ali, Chowdhury, Anupam, Maranas, Costas D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283520/
https://ncbi.nlm.nih.gov/pubmed/25601910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2014.00076
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