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Succinate Overproduction: A Case Study of Computational Strain Design Using a Comprehensive Escherichia coli Kinetic Model

Computational strain-design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models. In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations u...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Khodayari, Ali, Chowdhury, Anupam, Maranas, Costas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283520/
https://ncbi.nlm.nih.gov/pubmed/25601910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2014.00076
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