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Ectopic Ptf1a expression in murine ESCs potentiates endocrine differentiation and models pancreas development in vitro
Besides its role in exocrine differentiation, pancreas-specific transcription factor 1a (PTF1a) is required for pancreas specification from the foregut endoderm and ultimately for endocrine cell formation. Examining the early role of PTF1a in pancreas development has been challenging due to limiting...
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| Udgivet i: | Stem Cells |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283475/ https://ncbi.nlm.nih.gov/pubmed/24375815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1616 |
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