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Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover
Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of tum...
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| Опубликовано в: : | EMBO J |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BlackWell Publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283404/ https://ncbi.nlm.nih.gov/pubmed/25180228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489385 |
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