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Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover
Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of tum...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4283404/ https://ncbi.nlm.nih.gov/pubmed/25180228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489385 |
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