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Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of tum...

詳細記述

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書誌詳細
出版年:EMBO J
主要な著者: Hong, Xin, Nguyen, Hung Thanh, Chen, Qingfeng, Zhang, Rui, Hagman, Zandra, Voorhoeve, P Mathijs, Cohen, Stephen M
フォーマット: Artigo
言語:Inglês
出版事項: BlackWell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283404/
https://ncbi.nlm.nih.gov/pubmed/25180228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489385
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