The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels

The non-synonymous SNP rs2228145 in the IL6R gene on chromosome 1q21.3 is associated with a wide range of common diseases, including asthma, rheumatoid arthritis, type 1 diabetes and coronary heart disease. We examined the contribution of this functional IL6R gene polymorphism rs2228145 versus other...

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Detalhes bibliográficos
Publicado no:Behav Genet
Main Authors: van Dongen, Jenny, Jansen, Rick, Smit, Dirk, Hottenga, Jouke-Jan, Mbarek, Hamdi, Willemsen, Gonneke, Kluft, Cornelis, Penninx, Brenda W.J., Ferreira, Manuel A., Boomsma, Dorret I., de Geus, Eco J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283105/
https://ncbi.nlm.nih.gov/pubmed/24791950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-014-9656-8
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