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Neuronal influences are necessary to produce mitochondrial co-localization with glutamate transporters in astrocytes

Recent evidence suggests that the predominant astrocyte glutamate transporter, GLT-1/ Excitatory Amino Acid Transporter 2 (EAAT2) is associated with mitochondria. We used primary cultures of mouse astrocytes to assess co-localization of GLT-1 with mitochondria, and tested whether the interaction was...

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Publicat a:J Neurochem
Autors principals: Ugbode, Christopher I, Hirst, Warren D, Rattray, Marcus
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283053/
https://ncbi.nlm.nih.gov/pubmed/24814819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12759
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