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Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection

Sonic hedgehog (SHH) is a glycoprotein associated with development that is also expressed in the adult CNS and released after brain injury. Since the SHH receptors patched homolog‐1 and Smoothened are highly expressed on astrocytes, we hypothesized that SHH regulates astrocyte function. Primary mous...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Ugbode, Christopher I., Smith, Imogen, Whalley, Benjamin J., Hirst, Warren D., Rattray, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575469/
https://ncbi.nlm.nih.gov/pubmed/28485896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14064
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