PTEN Loss is Associated with Upgrading of Prostate Cancer from Biopsy to Radical Prostatectomy

When distinguishing between indolent and potentially harmful prostate cancers, the Gleason score is the most important variable, but may be inaccurate in biopsies due to tumor under-sampling. This study investigated whether a molecular feature, PTEN protein loss, could help identify which Gleason sc...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Lotan, Tamara L., Carvalho, Filipe LF., Peskoe, Sarah B., Hicks, Jessica L., Good, Jennifer, Fedor, Helen, Humphreys, Elizabeth, Han, Misop, Platz, Elizabeth A., Squire, Jeremy A., De Marzo, Angelo M., Berman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282985/
https://ncbi.nlm.nih.gov/pubmed/24993522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2014.85
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