Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer

PTEN (phosphatase and tensin homolog on chromosome 10) is one of the most frequently lost tumor suppressor genes in human cancers and it has been described in more than two-thirds of patients with advanced/aggressive prostate cancer. Previous studies suggest that, in prostate cancer, genomic PTEN lo...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Chaux, Alcides, Peskoe, Sarah B, Gonzalez-Roibon, Nilda, Schultz, Luciana, Albadine, Roula, Hicks, Jessica, De Marzo, Angelo M, Platz, Elizabeth A, Netto, George J
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380219/
https://ncbi.nlm.nih.gov/pubmed/22684219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2012.104
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