PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort

PTEN deletion is an established prognostic biomarker in prostate cancer. We compared PTEN immunohistochemistry (IHC) and PTEN fluorescence in situ hybridization (FISH) in the largest existing radical prostatectomy cohort with clinical follow-up data. There was high concordance between IHC and FISH:...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lotan, Tamara L., Heumann, Asmus, Rico, Sebastian Dwertmann, Hicks, Jessica, Lecksell, Kristen, Koop, Christina, Sauter, Guido, Schlomm, Thorsten, Simon, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630353/
https://ncbi.nlm.nih.gov/pubmed/29029453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19217
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