PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort

PTEN deletion is an established prognostic biomarker in prostate cancer. We compared PTEN immunohistochemistry (IHC) and PTEN fluorescence in situ hybridization (FISH) in the largest existing radical prostatectomy cohort with clinical follow-up data. There was high concordance between IHC and FISH:...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lotan, Tamara L., Heumann, Asmus, Rico, Sebastian Dwertmann, Hicks, Jessica, Lecksell, Kristen, Koop, Christina, Sauter, Guido, Schlomm, Thorsten, Simon, Ronald
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630353/
https://ncbi.nlm.nih.gov/pubmed/29029453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19217
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