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Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical Prostatectomy

African-American (AA) men have a higher risk of lethal prostate cancer (PCa) compared to European-American (EA) men. However, the molecular basis of this difference, if any, remains unclear. In EA PCa, PTEN loss, but not ERG rearrangement, has been associated with poor outcomes in most studies. Alth...

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Detalhes bibliográficos
Publicado no:Eur Urol
Main Authors: Tosoian, Jeffrey J., Almutairi, Fawaz, Morais, Carlos L., Glavaris, Stephanie, Hicks, Jessica, Sundi, Debasish, Humphreys, Elizabeth, Han, Misop, De Marzo, Angelo M., Ross, Ashley E., Tomlins, Scott A., Schaeffer, Edward M., Trock, Bruce J., Lotan, Tamara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274596/
https://ncbi.nlm.nih.gov/pubmed/27477529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2016.07.026
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