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Intramolecular isopeptide but not internal thioester bonds confer proteolytic and significant thermal stability to the S. pyogenes pilus adhesin Spy0125

Streptococcus pyogenes and other Gram-positive bacterial pathogens present long macromolecular filaments known as pili on their surface that mediate adhesion and colonization. These pili are covalent polymers, assembled by sortases. Typically, they comprise a putative adhesin at their tip, a backbon...

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Detaylı Bibliyografya
Yayımlandı:Proteins
Asıl Yazarlar: Walden, Miriam, Crow, Allister, Nelson, Miles D, Banfield, Mark J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282584/
https://ncbi.nlm.nih.gov/pubmed/24123467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24420
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