Peripheral natural killer cell maturation depends on the transcription factor Aiolos

Natural killer (NK) cells are an innate lymphoid cell lineage characterized by their capacity to provide rapid effector functions, including cytokine production and cytotoxicity. Here, we identify the Ikaros family member, Aiolos, as a regulator of NK-cell maturation. Aiolos expression is initiated...

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Vydáno v:EMBO J
Hlavní autoři: Holmes, Melissa L, Huntington, Nicholas D, Thong, Rebecca PL, Brady, Jason, Hayakawa, Yoshihiro, Andoniou, Christopher E, Fleming, Peter, Shi, Wei, Smyth, Gordon K, Degli-Esposti, Mariapia A, Belz, Gabrielle T, Kallies, Axel, Carotta, Sebastian, Smyth, Mark J, Nutt, Stephen L
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282578/
https://ncbi.nlm.nih.gov/pubmed/25319415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201487900
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