OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

Cristae, the organized invaginations of the mitochondrial inner membrane, respond structurally to the energetic demands of the cell. The mechanism by which these dynamic changes are regulated and the consequences thereof are largely unknown. Optic atrophy 1 (OPA1) is the mitochondrial GTPase respons...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Patten, David A, Wong, Jacob, Khacho, Mireille, Soubannier, Vincent, Mailloux, Ryan J, Pilon-Larose, Karine, MacLaurin, Jason G, Park, David S, McBride, Heidi M, Trinkle-Mulcahy, Laura, Harper, Mary-Ellen, Germain, Marc, Slack, Ruth S
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282575/
https://ncbi.nlm.nih.gov/pubmed/25298396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488349
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