The Mitochondrial Inner Membrane GTPase, Optic Atrophy 1 (Opa1), Restores Mitochondrial Morphology and Promotes Neuronal Survival following Excitotoxicity

Mitochondrial dynamics have been extensively studied in the context of classical cell death models involving Bax-mediated cytochrome c release. Excitotoxic neuronal loss is a non-classical death signaling pathway that occurs following overactivation of glutamate receptors independent of Bax activati...

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Bibliographic Details
Main Authors: Jahani-Asl, Arezu, Pilon-Larose, Karine, Xu, William, MacLaurin, Jason G., Park, David S., McBride, Heidi M., Slack, Ruth S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039390/
https://ncbi.nlm.nih.gov/pubmed/21041314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167155
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