SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here, we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hu...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: van der Lelij, Petra, Stocsits, Roman R, Ladurner, Rene, Petzold, Georg, Kreidl, Emanuel, Koch, Birgit, Schmitz, Julia, Neumann, Beate, Ellenberg, Jan, Peters, Jan-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282573/
https://ncbi.nlm.nih.gov/pubmed/25257309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488202
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