SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here, we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hu...

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Publicat a:EMBO J
Autors principals: van der Lelij, Petra, Stocsits, Roman R, Ladurner, Rene, Petzold, Georg, Kreidl, Emanuel, Koch, Birgit, Schmitz, Julia, Neumann, Beate, Ellenberg, Jan, Peters, Jan-Michael
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282573/
https://ncbi.nlm.nih.gov/pubmed/25257309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488202
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