SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here, we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hu...

Full description

Saved in:
Bibliographic Details
Published in:EMBO J
Main Authors: van der Lelij, Petra, Stocsits, Roman R, Ladurner, Rene, Petzold, Georg, Kreidl, Emanuel, Koch, Birgit, Schmitz, Julia, Neumann, Beate, Ellenberg, Jan, Peters, Jan-Michael
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282573/
https://ncbi.nlm.nih.gov/pubmed/25257309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488202
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items