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Structure of the Rad50 DNA double-strand break repair protein in complex with DNA
The Mre11–Rad50 nuclease–ATPase is an evolutionarily conserved multifunctional DNA double-strand break (DSB) repair factor. Mre11–Rad50's mechanism in the processing, tethering, and signaling of DSBs is unclear, in part because we lack a structural framework for its interaction with DNA in diff...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282560/ https://ncbi.nlm.nih.gov/pubmed/25349191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488889 |
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