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Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification
Endoderm cells undergo sequential fate choices to generate insulin-secreting beta cells. Ezh2 of the PRC2 complex, which generates H3K27me3, modulates the transition from endoderm to pancreas progenitors, but the role of Ezh2 and H3K27me3 in the next transition to endocrine progenitors is unknown. W...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282504/ https://ncbi.nlm.nih.gov/pubmed/25107471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488671 |
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