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Ligand binding and dynamics of the monomeric epidermal growth factor receptor ectodomain
The ectodomain of the human epidermal growth factor receptor (hEGFR) controls input to several cell signalling networks via binding with extracellular growth factors. To gain insight into the dynamics and ligand binding of the ectodomain, the hEGFR monomer was subjected to molecular dynamics simulat...
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| Pubblicato in: | Proteins |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282322/ https://ncbi.nlm.nih.gov/pubmed/23760854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24339 |
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