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Altering β-cell number through stable alteration of miR-21 and miR-34a expression

Aim: An insufficient functional β-cell mass is a prerequisite to develop diabetes. Thus, means to protect or restore β-cell mass are important goals in diabetes research. Inflammation and proinflammatory cytokines play important roles in β-cell dysfunction and death, and recent data show that 2 miRN...

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Bibliografske podrobnosti
izdano v:Islets
Main Authors: Backe, Marie Balslev, Novotny, Guy Wayne, Christensen, Dan Ploug, Grunnet, Lars Groth, Mandrup-Poulsen, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281945/
https://ncbi.nlm.nih.gov/pubmed/25483877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.27754
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