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Altering β-cell number through stable alteration of miR-21 and miR-34a expression
Aim: An insufficient functional β-cell mass is a prerequisite to develop diabetes. Thus, means to protect or restore β-cell mass are important goals in diabetes research. Inflammation and proinflammatory cytokines play important roles in β-cell dysfunction and death, and recent data show that 2 miRN...
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| Publicat a: | Islets |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281945/ https://ncbi.nlm.nih.gov/pubmed/25483877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.27754 |
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