A carregar...
Combining Valosin-containing Protein (VCP) Inhibition and Suberanilohydroxamic Acid (SAHA) Treatment Additively Enhances the Folding, Trafficking, and Function of Epilepsy-associated γ-Aminobutyric Acid, Type A (GABA(A)) Receptors
GABA(A) receptors are the primary inhibitory ion channels in the mammalian central nervous system. The A322D mutation in the α1 subunit results in its excessive endoplasmic reticulum-associated degradation at the expense of plasma membrane trafficking, leading to autosomal dominant juvenile myocloni...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281735/ https://ncbi.nlm.nih.gov/pubmed/25406314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580324 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|