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Pivotal Role of Extended Linker 2 in the Activation of Gα by G Protein-coupled Receptor
G protein-coupled receptors (GPCRs) relay extracellular signals mainly to heterotrimeric G-proteins (Gαβγ) and they are the most successful drug targets. The mechanisms of G-protein activation by GPCRs are not well understood. Previous studies have revealed a signal relay route from a GPCR via the C...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281731/ https://ncbi.nlm.nih.gov/pubmed/25414258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608661 |
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