ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding

Condensin, which contains two structural maintenance of chromosome (SMC) subunits and three regulatory non-SMC subunits, is essential for many chromosomal functions, including mitotic chromosome condensation and segregation. The ATPase domain of the SMC subunit comprises two termini connected by a l...

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Enregistré dans:
Détails bibliographiques
Publié dans:Open Biol
Auteurs principaux: Akai, Yuko, Kanai, Ryuta, Nakazawa, Norihiko, Ebe, Masahiro, Toyoshima, Chikashi, Yanagida, Mitsuhiro
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281712/
https://ncbi.nlm.nih.gov/pubmed/25520186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140193
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